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Complex treatments can work at any age

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By Lindsey Tanner
Posted on March 01, 2016

Irwin Weiner felt so good after heart surgery a few weeks before turning 90 that he stopped for a pastrami sandwich on the way home from the hospital. Dorothy Lipkin danced after getting a new hip at age 91. And at 94, William Gandin drives himself to the hospital for cancer treatments.

Jimmy Carter isn’t the only nonagenarian to withstand rigorous medical treatment. Very old age is no longer an automatic barrier for aggressive therapies — from cancer care like the former president has received, to major heart procedures, joint replacements and even some organ transplants.

In many cases, the nation’s most senior citizens are getting the same treatments given to people their grandchildren’s age — but with different goals.

Lipkin says having such major surgery at her age should be an individual decision.

Doctors agree. Some 90-year-olds are fitter than some 60-year-olds, but they say other considerations need to be in the mix.

At MD Anderson Cancer Center in Houston, the oldest patients are evaluated by geriatricians — specialists in medical care of the elderly — to make sure they’re able to tolerate harsh treatments. Physical and mental health are assessed. So is social support — whether there are family members or friends available to help during treatment and recovery.

“We do believe that cancer care should not be limited by age,” said Dr. Beatrice Edwards.

Less invasive treatments

While many elderly patients are healthy enough to tolerate conventional treatments, advances including more targeted, less toxic drugs and minimally invasive surgery techniques are opening the door to others.

Gandin, the 94-year-old, was diagnosed more than 10 years ago with prostate cancer. Treatment with radiation and chemotherapy failed to stop cancer from spreading to his lungs and bones. He’s now on hormone treatment that he said is controlling the disease.

A retired Exxon Mobil auditor, Gandin helps take care of his wife of 74 years in their assisted living home in Houston, and is not ready to give up on treatment. “I’m an eternal optimist — that’s what has carried me through,” he said.

Weiner, a retired furniture manufacturer representative, had a hardened, leaky aortic valve — a common condition in late life that can lead to disability and death. Open-heart surgery is a common option for heart-valve surgery, but some doctors hesitate to perform it in aged patients, said Kavinsky, the Chicago heart specialist.

Dr. Joseph Lamelas, Weiner’s surgeon at Mount Sinai Medical Center in Miami Beach, Florida, used a newer approach, implanting a new valve through a small incision on the right side of the chest.

After four days in the hospital last January, Weiner was back home in Boca Raton, Florida, and was well enough to have two big 90th birthday celebrations less than a month later.

Even transplants

Organ transplants are less common but not unheard of in the very old. Since 2013, there have been more than 100 kidney transplants in patients aged at least 80, including one in an 88-year-old, according to the United Network for Organ Sharing. Its records show that since 1987, the nation’s oldest kidney transplant recipient was a 96-year-old.

There are generally no strict age limits on transplants. Dr. Dorry Segev, a Johns Hopkins Medicine transplant specialist, said frailty is a more important factor, and his center measures it rigorously, including assessing patients’ grip strength, walking speed and muscle mass.

Ethical and financial issues complicate decisions on providing costly treatments to the very old, and life expectancy has to be considered, Kavinsky said.

“When you start doing procedures on a 90-year old, you have someone who has already exceeded the average lifespan in America,” he said. “How far should we go to keep them going?”

Dr. Joseph Dearani, chairman of cardiac surgery at the Mayo Clinic in Rochester, Minnesota, said a good gauge is whether treatment would likely help patients live well for at least another two years.

He said costs to the patient, their family and society also should be weighed, so that treatment is given to the right patients, and “for the most part, that happens.”

— AP

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