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What to eat to reduce risk of Alzheimer’s

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By: Andrew E. Budson, M.D.
Posted on: February 22, 2021

Would you like to reduce your risk of cognitive impairment, Alzheimer’s disease and dementia? Researchers from around the world have been studying a variety of different factors that might reduce these risks and keep the brain healthy.

Mediterranean diet still best

One factor that a number of studies have converged on is a Mediterranean-style diet. This diet includes fish, olive oil, avocados, fruits, vegetables, nuts, beans, whole grains and red wine in moderation.

Now, if you’re like me and you happen to like all these foods, then you have all the information you need to eat a brain-healthy diet.

On the other hand, if you’re not crazy about everything on the list, perhaps you would rather eat just the most important components. Researchers have, in fact, been trying to determine the key parts of this diet for a number of years.

For example, one study published in 2015 and updated in 2018 compared healthy older adults who followed a Mediterranean diet with extra olive oil or extra nuts versus one with a control reduced-fat diet. The enhanced Mediterranean diet groups fared equally well, and both had better cognitive performance outcomes than the reduced-fat diet group.

No study, however, has been able to determine the critical components of the Mediterranean diet that makes it so good for your brain — until now.

Fight loss of thinking power

Researchers at the National Institutes of Health published a study that evaluated the lifestyles of over 7,750 participants followed for five to 10 years.

Participants filled out questionnaires to determine their eating habits, and had cognitive tests of memory, language and attention administered over the phone.

Researchers used these data to determine the dietary factors most important in lowering risk of cognitive impairment, as well as the dietary factors most important in lowering risk of cognitive decline.

Let’s take a moment to define these terms. Let’s say you want to know what your risk is 10 years from now.

Cognition is a shorthand way of saying thinking, memory, language, attention, visuospatial and other mental abilities.

Your risk of cognitive impairment is the risk that, 10 years from now, your cognition will be worse than your peers.

Your risk of cognitive decline is the risk that, 10 years from now, your cognition will be worse than it is now.

Most important foods

What did the researchers find? Fish was the single most important dietary factor in lowering the risk of cognitive impairment. Vegetables were second best, and all other foods showed smaller, insignificant effects.

Moreover, of all the foods evaluated, only fish was associated with a lower risk of cognitive decline. Eating fish lowered the risk of both cognitive impairment and cognitive decline.

To reduce your risk of cognitive impairment and decline, eat a Mediterranean-style diet that includes fish several times per week.

There are lots of good fish to eat, including Atlantic mackerel, black sea bass, catfish, clams, cod, crab, crawfish, flounder, haddock, lobster, salmon, sardines, scallops, shrimp, skate, sole, squid, tilapia, trout and canned light tuna.

Just be careful about fish that may have high levels of mercury, such as swordfish and bigeye tuna; these fish should only be eaten occasionally. The FDA has a good guide to help you know the best fish to eat: See fda.gov/fishadvice.

Your mother was right

Did your mother ever tell you that fish was good for you? Mine did. In fact, she always used to say, “Fish helps you think.” She knew it all along; it just took the scientific community 50 years to catch up to her and prove it.

Andrew E. Budson, M.D., is a contributor to Harvard Health Publications. © 2020 Harvard University. Distributed by Tribune Content Agency, LLC.

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